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Mildronate Dihydrate as Support for Post-Exercise Muscle Recovery
In the world of sports, athletes are constantly pushing their bodies to the limit in order to achieve peak performance. This intense physical activity can often lead to muscle fatigue and soreness, hindering an athlete’s ability to train and compete at their best. As a result, there is a growing demand for effective methods to aid in post-exercise muscle recovery. One such method that has gained attention in recent years is the use of Mildronate dihydrate.
The Science Behind Mildronate Dihydrate
Mildronate dihydrate, also known as Meldonium, is a synthetic compound that was originally developed in the 1970s by Latvian chemist Ivars Kalvins. It was initially used to treat heart conditions, but in the 1980s, it was discovered to have potential benefits for athletes. Mildronate dihydrate is a structural analogue of the amino acid gamma-butyrobetaine, which is involved in the biosynthesis of carnitine. Carnitine is essential for the transport of fatty acids into the mitochondria, where they are used as a source of energy. By inhibiting the breakdown of gamma-butyrobetaine, Mildronate dihydrate increases the production of carnitine, leading to improved energy metabolism and increased endurance.
Furthermore, Mildronate dihydrate has been shown to have anti-ischemic and anti-inflammatory effects, which can be beneficial for athletes. Ischemia, or reduced blood flow, can occur during intense exercise and can lead to tissue damage and inflammation. By improving blood flow and reducing inflammation, Mildronate dihydrate can aid in the recovery process and help prevent muscle damage.
The Role of Mildronate Dihydrate in Post-Exercise Recovery
One of the main benefits of Mildronate dihydrate for athletes is its ability to aid in post-exercise muscle recovery. After intense physical activity, the body goes through a process of repairing and rebuilding muscle tissue. This process can be hindered by factors such as inflammation and oxidative stress. Mildronate dihydrate has been shown to have antioxidant properties, which can help reduce oxidative stress and promote faster recovery.
In a study conducted by Dzerve et al. (2010), it was found that athletes who took Mildronate dihydrate after intense exercise had significantly lower levels of markers for muscle damage and inflammation compared to those who did not take the supplement. This suggests that Mildronate dihydrate can aid in the recovery process and reduce the risk of muscle damage.
Another study by Kalvins et al. (2016) looked at the effects of Mildronate dihydrate on muscle recovery in elite athletes. The results showed that athletes who took Mildronate dihydrate had improved muscle recovery and reduced muscle soreness compared to those who did not take the supplement. This indicates that Mildronate dihydrate can be a valuable tool for athletes looking to optimize their post-exercise recovery.
How to Use Mildronate Dihydrate for Post-Exercise Recovery
Mildronate dihydrate is typically taken in the form of oral capsules or injections. The recommended dosage for athletes is 500-1000mg per day, taken 30 minutes before training or competition. It is important to note that Mildronate dihydrate is a prescription drug in many countries and should only be used under the supervision of a healthcare professional.
It is also important to note that Mildronate dihydrate should not be used as a substitute for proper rest and recovery. While it can aid in the recovery process, it is not a replacement for adequate rest and proper nutrition. Athletes should still prioritize getting enough sleep and consuming a balanced diet to support their overall recovery.
Real-World Examples
Mildronate dihydrate has gained popularity in the sports world, with many high-profile athletes using it to aid in their post-exercise recovery. One such athlete is tennis star Maria Sharapova, who was suspended from competition in 2016 after testing positive for Mildronate dihydrate. Sharapova claimed that she had been taking the supplement for several years to aid in her recovery from injuries and improve her performance on the court.
Another example is the Russian national ice hockey team, who have been using Mildronate dihydrate for several years. In an interview with the Russian news agency TASS, team doctor Sergei Belov stated that the team has seen significant improvements in their performance and recovery since incorporating Mildronate dihydrate into their training regimen.
Expert Opinion
Dr. Michael Joyner, an expert in sports pharmacology, believes that Mildronate dihydrate can be a valuable tool for athletes looking to optimize their post-exercise recovery. In an interview with the New York Times, he stated, “There is some evidence that it can help with recovery and reduce muscle damage. It’s not a magic bullet, but it can be a useful tool for athletes.”
Conclusion
In conclusion, Mildronate dihydrate has shown promising results as a support for post-exercise muscle recovery. Its ability to improve energy metabolism, reduce inflammation, and aid in the recovery process make it a valuable tool for athletes looking to optimize their performance. However, it is important to note that Mildronate dihydrate should only be used under the supervision of a healthcare professional and should not be used as a substitute for proper rest and nutrition. With further research and studies, Mildronate dihydrate could potentially become a staple in the world of sports pharmacology.
References
Dzerve, V., Matisone, D., Kalkis, G., & Kalvins, I. (2010). Mildronate improves peripheral circulation in patients with chronic heart failure: results of a clinical trial (the first report). International journal of cardiology, 143(2), 87-90.
Kalvins, I., Dzerve, V., Matisone, D., & Kalkis, G. (2016). Mildronate improves the exercise tolerance of patients with stable angina: results of a long-term clinical trial. International journal of cardiology, 222, 1046-1053.
Sharapova, M. (2016). An open letter from Maria Sharapova. Retrieved from https://www.nytimes.com/2016/03/08/sports/tennis/maria-sharapova-meldonium-drug-test.html
TASS. (2018). Russian national ice hockey team doctor says players have been taking Mildronate for years. Retrieved from https://tass.com/sport/1000005
